Maya Rudolph has left the production company she founded with Natasha Lyonne after five years of working together. 

The actresses have had success with their collaboration, launching Rudolph's Loot on AppleTV+ and Lyonne's Poker Face on Peacock, among other titles.

In a statement, the Saturday Night Live alum, 51, and the Russian Doll star, 44, said the split is amicable.

'Moving forward, Natasha will operate under the name Animal Pictures while Maya will produce independently,' a statement obtained by Deadline read.

'We will continue to support each other and remain committed to the various projects we've developed together and have in the pipeline. We are excited for each other and what the future holds.'

They formed their production company in 2018 alongside producer Danielle Renfrew Behrens, who served as President. 

They recently got Season 2 renewals for both Loot and Poker Face. Lyonne received four Emmy nominations for her participation in the series. 

She plays a human lie detector turned detective named Charlie Cale in the gripping 10-part series, created by Knives Out director Rian Johnson.

Her character uses her finely tuned truth-discerning abilities to investigate a murder and also stars Benjamin Bratt, Chloë Sevigny and Adrien Brody.

On Loot, Rudolph plays Molly, a billionaire who decides to become a philanthropist after her billionaire husband leaves her for a younger woman. 

The series also stars Adam Scott, Michaela Jaé Rodriguez, Joel Kim Booster, Nat Faxon and Ron Funches. 

Animal Pictures also produced Netflix's Russian Doll, which was co-created by and stars Lyonne as well as the coming-of-age Hulu series Crush.

The production company also made Sirens, a music documentary about an all-female heavy medal band from Beirut.

Animal Pictures still has a number of projects still in the pipeline including Extra Ordinary, which is based on an Irish film created by Mike Ahern and Enda Loughman.

Desert People, created by Alia Shawkat and Lyonne is another project in development. It is largely based on Shawkat's life.  

Rudolph will continue to voice several characters in the eighth and final season of Big Mouth on Netflix as well as tour with her Prince tribute band Princess.

She has also been slated to perform a voice role alongside John Krasinski and Ryan Reynonds in the fantasy comedy Imaginary Friends, which will start streaming on Paramount on May 24, 2024.

Meanwhile, Lyonne stars in Azazel Jacob’s indie drama His Three Daughters, which Netflix acquired at the Toronto International Film Festival for just under $7 million.

The film also stars Elizabeth Olsen, Carrie Coon and Jovan Adepo.