. .
.
. . *, ,
. . *,
. . *
. . **,
. . ***,
* ,
** ,
*** -,
, , 60
-
, .
,
, [13].
(Anisakis simplex) ,
Anisakidae. nisakis simplex (. simplex)
Pseudoterranova decipiens ,
[15].
. simplex ( ), Pseudoterranova
Pseudoterranova decipiens, Phocanema ( ),
Contracaecum, Hysterothylacium
.
, Anisakidae,
Anisakis
Pseudoterranova [1].
. simplex
.
(, )
. simplex, (, ,
) P. decipiens [13].
,
.
( ), ,
( ),
(
/ ).
, , ,
. ,
( )
, .
- .
simplex, , ,
.
. ,
, -
.
, ,
[13]. ∼20 000
90% ,
, [2].
, [13].
,
[35]. -
. , 98% 94%
[1]. Pseudoterranovosis
, (
, , ) [1].
,
[1].
(, ), . ,
, ,
, , [15]. .
simplex
(-20 2 C 11 ),
t -50 C -60 C 11 1
[6].
,
[1]. ( )
. ,
, . simplex ,
[7].
: . simplex
: 0,4% 22%
[8]. 10% [9].
,
[15].
, sIgE . simplex ,
,
(, , , ).
, (
64,786%) sIgE
[911]. ,
(, )
[3].
- (
; , sIgE . simplex,
, 1
. .) [13].
, 1622%
sIgE [12].
sIgE . simplex,
, [13].
( sIgE
) ,
, ,
- [15].
:
,
[14].
: 1) ; 2)
; 3) (
); 4) (, )
; 5)
- - (
)
[16, 9]. sIgG1? -
- ,
, , [15].
- IgM, IgA,
IgE IgG
.
( ),
46 ,
sIgE [13]. M. Caballero ., sIgE
. simplex 1 2 (ImmunoCap)
(66,7%), ≥ 4
(95,2%) [9].
rAni s 1, Escherichia coli,
, 100%
in vivo in vitro
[14]. sIgE rAni s 1 90%
sIgE Anisakis (≤ 0,6 /) [3].
. 9 .
simplex, Ani s 1 Ani s 7
[24].
(100%), 61,1% 93,9% ni s 1
Ani s 7 [1]. 86%
sIgE Ani s 1 [1, 15]. ,
, 100%
[1]. Ani s 2 () Ani s 3 ()
. simplex,
. ,
. sIgE Ani s 3
, , .
. simplex
100% [6].
: -
10 [1].
, ,
[1].
, 30%
[13, 9].
, ( ) [9].
. simplex
:
;
, - /
sIgE . simplex [15]. ,
-
. , , 6
. . simplex
, 1936 0,30,6 , ,
Y- . , P. decipiens
- , (2550 ) (0,31,2 ) [2].
,
, ,
,
[1, 16].
. ,
/ . :
.
, [1, 16].
, /
[16]. .
: ,
, [14].
(
, 1/224 )
, , , ;
, [1, 17].
,
,
[2]. , .
a
, 57
.
, [1, 5].
(
). ,
, [16].
, , a
,
( ), ,
, , ( )
[1].
,
(
). . simplex,
[15]. , 0,524
/ , ,
. 61-
[18].
sIgE . simplex,
.
IgE-
(, , ,
), 2
.
P. decipiens .
.
, Pseudoterranova,
(
≤ 48 ).
(
(, ) (, ),
;
)
[1, 17].
:
sIgE . simplex
[17].
,
[1]. a
, .
, . simplex
[19]. , ,
( ),
(
sIgE ) sIgE .
simplex ( ) [19].
a -
,
.
, , (
), ,
.
, .
a.
,
12 .
,
, .
,
. ,
(400800 621 )
[1, 5].
/ (, ),
a .
a
,
[15].
[1].
, 20 C
7 ( 4 ) 35 C ≥ 15 [1].
.
,
. ,
20% [1, 17].
. , 11 ,
- , , ,
. , ,
6 . ,
, .
3228%. .
.
,
. .
.
, ,
,
. - .
,
, ()
. .
,
,
. IgG- .
simplex (1,8 ..). IgE
A. simplex .
10 .
: , 4%.
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